Caryophyllene Strains: What Are They Used For?

Caryophyllene Strains

Caryophyllene, also called beta or b-caryophyllene, is one of the common terpenes in marijuana. It has been regarded for its herbal, spicy taste with woody hints. Caryophyllene is also available in cinnamon, hops, and black pepper. 

As a terpene present in weed, caryophyllene has strong healing potential, given that it comes with antiseptic, antifungal, antibacterial, and anticancer properties. Caryophyllene is unique as it can interact with the CBD cannabinoid receptor of the endocannabinoid system. It quickly works and does the job after one consumed it orally. So, you may want to check out the popular caryophyllene strains and see how powerful they can be. 

Caryophyllene – What Is It?

Known as a dietary cannabinoid, caryophyllene is a typical organic food additive. Its color is pale yellow, and its taste is sweet. Caryophyllene is available in food items such as fig and allspice. It is among the most completely studied and researched terpenes that exist in marijuana. 

E.J. Corey, an organic chemist, and researcher from Harvard, studied this terpene in the 1960s and discovered its unique properties. His pioneering study assisted the modern-day scientists in examining the potential medicinal uses of caryophyllene. 

Moreover, this particular terpene is also available in different aromatic oils such as clove and rosemary oil. It can also be found in basil, oregano, and cloves. Caryophyllene is the one behind the slight kick of potency linked to smelling the smashed pepper. 

Caryophyllene is larger than other terpenes such as limonene and myrcene. Its molecular structure features the rare cyclobutene ring that you may not be able to find in other cannabis terpenes.

The endocannabinoid system of the human body comes with a large group of receptors scattered all over your body. There are 2 major types of receptors: the CB1 and CB2. The CB1 receptors are situated primarily in the human brain and CNS. The CB2 receptors, however, can be found in the peripheral organs. 

If a cannabinoid like THC has been consumed, it will directly bind to the CB1 receptors in the central nervous system and brain, causing a person to feel euphoric. The distinct molecular formation of caryophyllene lets it quickly bind to the CB2 receptors of your peripheral endocannabinoid system. Meaning, it does not cause any euphoric sensation while giving more of the benefits related to those receptors. One of these is reduced inflammation. 

Caryophyllene seems to be special than other terpenes. That’s mainly because it’s the only terpene that can automatically activate the cannabinoid receptors, which is true for CB2 receptors. 

How Does the Caryophyllene Smell?

This particular terpene comes with a strong, peppery, and spicy scent. It can be the active ingredient in most essential oils that have the same aroma profiles. Rosemary, black caraway, ylang-ylang, basil, and clove are some of the essential oils high in caryophyllene. 

Clove essential oil is famous for its superb numbing effect for pain like toothaches. The ylang-ylang essential oil made with those tropical trees that can be found in India is usually mixed with perfumes. This special oil is widely used in various religious ceremonies in some areas in Asia. 

Uses of Caryophyllene

Do you love to cook spicy food? If that is your case, then you probably encountered this terpene even for once. Recipes ranging from pepper steak to cinnamon French toast might contain caryophyllene. This terpene comes with preservative properties and can stabilize and flavor beer. 

Beer has been the most famous drink to have hops, but other drinks can also have it. Hopped whiskeys and other kinds of vodka can also contain hops that are rich in caryophyllene. Caryophyllene is also used as a flavoring in chewing gums that boosts their spicy or citrusy taste. Detergents and various topical skincare products can also contain this terpene. 

Famous Caryophyllene Strains of Cannabis

There are several marijuana strains with caryophyllene. Those strains that have higher amounts of caryophyllene are more likely to be musky and spicy. Some of them even have that jazzy profile. 

Many of them have prominent fuel and diesel notes that tend to trigger a tingling sensation on the nose, which is the same with how you react when inhaling pepper. Outlined below are those cannabis strains that contain higher levels of caryophyllene:

  • Bubba Kush
  • GSC
  • Sour Diesel
  • Candyland
  • Chemdawg
  • Original Glue
  • Death Star
  • Cookies and Cream
  • The White
  • Gelato
  • Master Kush

Caryophyllene is also available in higher amounts in most strains that are part of the Cookies Family. Examples are the Girl Scout Cookies, Platinum GSC, Candyland, and Cookies and Cream. Caryophyllene is a great stress reliever that also exists in different hybrids regarded to trigger anxiety and relaxation. With its unique fragrant notes, it is quite quick to check and see in a cannabis strain.

A lot of cannabis salves and topicals use those mentioned cannabis strains that rich in caryophyllene. It showcases its organic aromatic profile while giving some healing benefits. 

Caryophyllene and Its Possible Benefits

Studies conducted about caryophyllene also indicated a wide array of healing potential. A 2014 study reveals the pain-killing properties of this terpene in rats, and another study involving rats shows its potential to decrease alcohol intake. It makes caryophyllene a good treatment for alcohol treatment. 

Caryophyllene seems to have anti-inflammatory and antioxidant properties and to become a probable therapy for relieving inflammatory bowel disease. Research even discovered that caryophyllene might help relieve depression and anxiety. 

Current studies look forward to discovering and unveil more of its potential healing effect. These include the research that indicated its capability to help in dealing with gene stress that inhibits and affects lifespan longevity. 


The famous caryophyllene strains are sure to deliver the best of this terpene as a therapeutic agent. Truly, terpenes are extraordinary not just because they add an aromatic scent and mouth-watering flavor to cannabis, but they offer the best possible healing effects. Caryophyllene is indeed a good example of a superb terpene that stands out not just in taste but also in healing potential. So, enjoy the caryophyllene-rich cannabis strains and see.